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Selected Publications

 

1:

Gunasekera AM, Myrick A, Militello KT, Sims JS, Dong CK, Gierahn T, Le Roch K, Winzeler E, Wirth DF.

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Regulatory motifs uncovered among gene expression clusters in Plasmodium falciparum.
Mol Biochem Parasitol. 2007 May;153(1):19-30. Epub 2007 Jan 18.
PMID: 17307259 [PubMed - in process]

 

2:

Kidgell C, Volkman SK, Daily J, Borevitz JO, Plouffe D, Zhou Y, Johnson JR, Le Roch K, Sarr O, Ndir O, Mboup S, Batalov S, Wirth DF, Winzeler EA.

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A systematic map of genetic variation in Plasmodium falciparum.
PLoS Pathog. 2006 Jun;2(6):e57. Epub 2006 Jun 23.
PMID: 16789840 [PubMed - indexed for MEDLINE]

 

3:

Young JA, Fivelman QL, Blair PL, de la Vega P, Le Roch KG, Zhou Y, Carucci DJ, Baker DA, Winzeler EA.

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The Plasmodium falciparum sexual development transcriptome: a microarray analysis using ontology-based pattern identification.
Mol Biochem Parasitol. 2005 Sep;143(1):67-79.
PMID: 16005087 [PubMed - indexed for MEDLINE]

 

4:

Daily JP, Le Roch KG, Sarr O, Ndiaye D, Lukens A, Zhou Y, Ndir O, Mboup S, Sultan A, Winzeler EA, Wirth DF.

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In vivo transcriptome of Plasmodium falciparum reveals overexpression of transcripts that encode surface proteins.
J Infect Dis. 2005 Apr 1;191(7):1196-203. Epub 2005 Feb 28.
PMID: 15747257 [PubMed - indexed for MEDLINE]

 

5:

Le Roch KG, Johnson JR, Florens L, Zhou Y, Santrosyan A, Grainger M, Yan SF, Williamson KC, Holder AA, Carucci DJ, Yates JR 3rd, Winzeler EA.

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Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle.
Genome Res. 2004 Nov;14(11):2308-18.
PMID: 15520293 [PubMed - indexed for MEDLINE]

 

6:

Daily JP, Le Roch KG, Sarr O, Fang X, Zhou Y, Ndir O, Mboup S, Sultan A, Winzeler EA, Wirth DF.

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In vivo transcriptional profiling of Plasmodium falciparum.
Malar J. 2004 Aug 5;3:30.
PMID: 15296511 [PubMed - indexed for MEDLINE]

 

7:

Sam-Yellowe TY, Florens L, Johnson JR, Wang T, Drazba JA, Le Roch KG, Zhou Y, Batalov S, Carucci DJ, Winzeler EA, Yates JR 3rd.

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A Plasmodium gene family encoding Maurer's cleft membrane proteins: structural properties and expression profiling.
Genome Res. 2004 Jun;14(6):1052-9. Epub 2004 May 12.
PMID: 15140830 [PubMed - indexed for MEDLINE]

 

8:

Le Roch KG, Zhou Y, Blair PL, Grainger M, Moch JK, Haynes JD, De La Vega P, Holder AA, Batalov S, Carucci DJ, Winzeler EA.

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Discovery of gene function by expression profiling of the malaria parasite life cycle.
Science. 2003 Sep 12;301(5639):1503-8. Epub 2003 Jul 31.
PMID: 12893887 [PubMed - indexed for MEDLINE]

 

9:

Merckx A, Le Roch K, Nivez MP, Dorin D, Alano P, Gutierrez GJ, Nebreda AR, Goldring D, Whittle C, Patterson S, Chakrabarti D, Doerig C.

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Identification and initial characterization of three novel cyclin-related proteins of the human malaria parasite Plasmodium falciparum.
J Biol Chem. 2003 Oct 10;278(41):39839-50. Epub 2003 Jul 17.
PMID: 12869562 [PubMed - indexed for MEDLINE]

 

10:

Le Roch KG, Zhou Y, Batalov S, Winzeler EA.

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Monitoring the chromosome 2 intraerythrocytic transcriptome of Plasmodium falciparum using oligonucleotide arrays.
Am J Trop Med Hyg. 2002 Sep;67(3):233-43.
PMID: 12408661 [PubMed - indexed for MEDLINE]

 

11:

Volkman SK, Hartl DL, Wirth DF, Nielsen KM, Choi M, Batalov S, Zhou Y, Plouffe D, Le Roch KG, Abagyan R, Winzeler EA.

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Excess polymorphisms in genes for membrane proteins in Plasmodium falciparum.
Science. 2002 Oct 4;298(5591):216-8.
PMID: 12364807 [PubMed - indexed for MEDLINE]

 

12:

Li Z, Le Roch K, Geyer JA, Woodard CL, Prigge ST, Koh J, Doerig C, Waters NC.

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Influence of human p16(INK4) and p21(CIP1) on the in vitro activity of recombinant Plasmodium falciparum cyclin-dependent protein kinases.
Biochem Biophys Res Commun. 2001 Nov 16;288(5):1207-11.
PMID: 11700040 [PubMed - indexed for MEDLINE]

 

13:

Dorin D, Le Roch K, Sallicandro P, Alano P, Parzy D, Poullet P, Meijer L, Doerig C.

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Pfnek-1, a NIMA-related kinase from the human malaria parasite Plasmodium falciparum Biochemical properties and possible involvement in MAPK regulation.
Eur J Biochem. 2001 May;268(9):2600-8.
PMID: 11322879 [PubMed - indexed for MEDLINE]

 

14:

Knockaert M, Gray N, Damiens E, Chang YT, Grellier P, Grant K, Fergusson D, Mottram J, Soete M, Dubremetz JF, Le Roch K, Doerig C, Schultz P, Meijer L.

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Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors.
Chem Biol. 2000 Jun;7(6):411-22.
PMID: 10873834 [PubMed - indexed for MEDLINE]

 

15:

Le Roch K, Sestier C, Dorin D, Waters N, Kappes B, Chakrabarti D, Meijer L, Doerig C.

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Activation of a Plasmodium falciparum cdc2-related kinase by heterologous p25 and cyclin H. Functional characterization of a P. falciparum cyclin homologue.
J Biol Chem. 2000 Mar 24;275(12):8952-8.
PMID: 10722743 [PubMed - indexed for MEDLINE]

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