LeRochLabLogo

Our Team

Karine outside the lab

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Coy Nadia

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Code! Code! Code!

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Welcome to the Le Roch Lab

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Smile, Jacques :)

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I've got something!!

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Data Jeff, Data!

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I did something bad!

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I WILL clone this!!

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Hi there!!

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Karine w/ her parasites

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I LOVE malaria!

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Don't spy!

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Plasmodium is beautiful!

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I'm really concentrating...

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Principle Investigator

KarineLeRoch
Dr. Karine Leroch, Ph.D.

Karine Le Roch, Ph.D.
Assistant Professor
karine.leroch@ucr.edu
Phone: 951 827 5422
Fax: 951 827 3087

 

Dr. Le Roch received her BA. in 1995 from the University of Paris VI, France, where she majored in Biochemistry, Molecular Biology, Microbiology and Endocrinology.

Dr. Le Roch did an internship in a European exchange programme (Erasmus) in North Wales University, UK with Prof. M. Doenhoff where she worked on a larval stage protein of the human parasite, Schistosoma mansoni, a disease that affects more than 200 million people each year.

Dr. Le Roch obtained a master’s degree in Parasitology at the University of Lille II, France and the University of Oxford, U.K. in 1997. As a master’s student, She worked at the Institute of Molecular Medicine, John Radcliff Hospital, Oxford, UK with Dr. A. E. Wakefield. Her research focused on the genetic diversity of Pneumocystis carinii, a parasite infecting the lungs of immuno-suppressed patients.

She completed her Ph.D. in June 2001 at the University of Paris VI, France, under the supervision of Prof C. Deorig. Her research focused on the cell cycle regulation of the human malaria parasite, Plasmodium falciparum, and more specifically on cyclin dependant kinases to develop novel therapeutic approaches against the malaria parasite.

In 2001, as a postdoctoral fellow, she joined the Scripps Research Institute, San Diego, California and worked with Dr. E. Winzeler to set up the functional analysis of the P. falciparum genome using microarray technology. At that time, she worked in a close collaboration with the Genomics Institute of the Novartis Research Foundation (GNF, San Diego, California) to develop a new array technology for the screening of protease inhibitors in an effort to discover novel treatments. She joined GNF in January 2004 where she developed the malaria drug discovery program.

Since April 2006 at UCR, Dr. Le Roch research focuses on developing biological tools ex vivo to dissect the molecular events involved in the ubiquitin / proteasome pathway throughout the life cycle of P. falciparum. Using functional genomics approaches such as proteomics, She expect to elucidate critical regulatory networks driving the life cycle progression of the malaria parasite and identify novel drug targets against this devastating disease.


 

Lab Members



Research Assistants

Jacques Prudhomme
Jacques Prudhomme

Email: jacques@ucr.edu
Phone: 951 827 5934
Biological Sciences Building Room 3210

 

 

 

 

 

 

 

 

Postdoctoral Fellows

Nadia Ponts
Nadia Ponts, PhD

Email: nadia.ponts@ucr.edu
Phone: 951 827 5934

 

 

 

 

 

 

 

 

Graduate Students

Jeff Yang
Jianfeng (Jeff) Yang

Email: yangjianfeng@gmail.com

Bio: Currently I am a graduate student at CSE@UCR. I have a masters' degree from EE@THU and bachelors' degree from EE@USTC. My research interests include but are not limited to statistics, computation, information theory, AI, philosophy and their applications, especially in biology, economics, engineering and management. My hobbies are fishing, basketball, talking with my friends and thinking. Refer to my web site for more information.

 

 

Undergraduate Students

Ecir McDandiel
Eric McDaniel
Undergraduate of Biology & Biochemistry

emcda001@student.ucr.edu

 

 

 

 

 

 

 

 

 

 

jesephYacoub
Joseph Yacoub
Undergraduate of Neurobiology

jyaco002@student.ucr.edu

 

 

 

 

 

 

 

 

 

Visiting Scholar

randymaile
Randal Maile
Consultant and Webmaster

rmaile2000@yahoo.com

 

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