File: <sindbisvirus.htm> <General Index> Site Description Glossary <Navigate
to Home>
|
SINDBIS VIRUS (Contact) Please CLICK on
underlined links for details: Sindbis Virus
is a member of the Togaviridae group
of alphaviruses. It was first isolated in Egypt in
1952. Infection results in a fever
and arthralgia, rash and malaise. The
virus occurs primarily in Southern and Eastern Africa, Egypt, Palestine, the
Philippines and portions of Australia.
Being an arthropod-borne virus it occurs in nature through
transmission between bird hosts and Culex
spp. mosquito vectors.
Humans become infected from the bites of infected mosquitoes. The virus has also been linked to Pogosta Disease in Finland, Ockelbo Disease
in Sweden and Karelian Fever in
Russia. CONTROL No vaccine or prophylactic medication is available for
infection with Sindbis Virus.
Prevention involves protective measures against mosquitoes in areas with
known virus circulation, including appropriate clothing (long sleeves and
trousers) and the application of insect repellent on exposed skin. = = = = = = = = = = = = = = = = = =
= = Key References: <medvet.ref.htm> <Hexapoda> Cao, S. & W. Zhang. 2013. Characterization of an early-stage fusion intermediate of
Sindbis virus using cryoelectron microscopy.
Proc. Natl. Acad. Sci. 110(33): 13362-13367. Frolov, I., R. Hardy & C. M. Rice. 2001.
Cis-acting RNA elements at the 5' end of Sindbis virus genome RNA
regulate minus and plus-strand RNA synthesis. RNA 7(11): 1638-1651. Kurkela, S., T. Manni, A. Vaheri &
O. Vapalahti. 2004. Causative agent of Pogosta disease
isolated from blood and skin lesions.
Emerg. Infect. Disease. Matheson, R. 1950. Medical Entomology. Comstock Publ. Co, Inc. 610 p. Service, M. 2008.
Medical Entomology For Students.
Cambridge Univ. Press. 289 p Legner, E. F. 1995. Biological control of Diptera of medical and veterinary
importance. J. Vector Ecology 20(1):
59_120. Legner, E. F. 2000.
Biological control of aquatic Diptera. p. 847_870.
Contributions to a Manual of Palaearctic Diptera, Vol. 1, Science Herald, Budapest. 978 p. |